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Cell. 2007 Dec 14;131(6):1032-4.

Autophagy and cell death: no longer at odds.

Author information

1
The University of Texas MD Anderson Cancer Center, Department of Biochemistry and Molecular Biology, 1515 Holcombe Boulevard-Unit 1000, Houston, TX 77030, USA. abergman@mdanderson.org

Abstract

Autophagy has been associated with both cell survival and cell death, but the role of autophagy in cell death has been controversial. In this issue, Berry and Baehrecke (2007) report that autophagy is involved in physiological cell death during Drosophila development and is controlled by similar mechanisms as those that control its function in cell survival.

PMID:
18083090
PMCID:
PMC2502067
DOI:
10.1016/j.cell.2007.11.027
[Indexed for MEDLINE]
Free PMC Article
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