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Zh Vyssh Nerv Deiat Im I P Pavlova. 2007 Sep-Oct;57(5):613-7.

[Behavior of mice from different strains: modifications produced by noopept].

[Article in Russian]

Abstract

Genotype-dependent behavioral effects were demonstrated in BALB/c, C57BL/6J [Russian character: see text] DBA/2J mice after injections of nootropic drug Noopept. In an elevated plus maze, drug administration induced an increase in the number of enterings into bright arms in BALB/c mice, whereas the opposite effect was observed in C57BL/6J. After the Noopept administration, animals from all the three strains increased the number of active avoidance reactions in stress-inducing slip-funnel test. A significant intensification of exploration behavior was observed in a closed plus-maze in BALB/c and C57BL/6J. The Noopept affected weakly or had no effect on the behavior of DBA/2J mice.

PMID:
18064900
[Indexed for MEDLINE]

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