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Epidemiol Infect. 2008 Nov;136(11):1492-5. Epub 2007 Dec 7.

Sexual dimorphism in campylobacteriosis.

Author information

1
School of Biological Sciences, University of Aberdeen, Cruickshank Building, Aberdeen, UK. n.strachan@abdn.ac.uk

Abstract

Sexual dimorphism in infectious diseases whereby disease incidence is more prevalent in one gender has been reported repeatedly in the scientific literature. Both behavioural and physiological differences have been suggested as a cause of this gender bias but there is a paucity of data to support either of these viewpoints. Here it is hypothesized that for campylobacteriosis physiological factors play an important role in the higher incidence in males. We demonstrate in the human population (from several countries in three continents) that this bias exists in young children (<1 year) where behavioural differences between genders are likely to be minimal. Further we demonstrate this difference in an animal model where both infection rates and shedding rates of the organism are greater in male mice.

PMID:
18062834
PMCID:
PMC2870750
DOI:
10.1017/S0950268807009934
[Indexed for MEDLINE]
Free PMC Article

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