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Horm Res. 2008;69(2):107-13. Epub 2007 Dec 5.

Type 2 diabetes in children and adolescents in a 2-year follow-up: insufficient adherence to diabetes centers.

Author information

1
Vestische Hospital for Children and Adolescents, University of Witten/Herdecke, Datteln, Germany. T.Reinehr@kinderklinik-datteln.de

Abstract

BACKGROUND/AIMS:

To study the 2-year course of children and adolescents with type 2 diabetes mellitus (T2DM) in general practice to present (1) the treatment modalities, (2) patient adherence, and (3) the occurrence of comorbidities.

METHODS:

HBA1c, lipids, blood pressure, treatment modalities, occurrence of retinopathy and nephropathy were analyzed in 129 children and adolescents with T2DM (median age 13.4 years, 75% female) in specialized diabetes centers in Germany.

RESULTS:

Seventy-eight (60%) children dropped out of care after a mean of 7.1 months. Drug treatment was not stopped in any of the 64 children initially treated with antidiabetic drugs. Sixteen (12%) children were treated solely by lifestyle intervention over the 2-year course. In the 51 children with complete follow-up, median HbA1c was 7.7% at diagnosis and 6.3% after 2 years. Less than 5% of all children were treated with antihypertensive or lipid-lowering drugs, while 65% suffered from hypertension and 44% from dyslipidemia. Over the course of the disease, retinopathy was not observed, while microalbuminuria occurred in 25%.

CONCLUSIONS:

In general practice, many children and adolescents with T2DM were lost of follow-up. Lifestyle intervention as sole treatment was not often useful for long-term metabolic control. Dyslipidemia and hypertension were seldom treated as recommended.

PMID:
18059091
DOI:
10.1159/000111814
[Indexed for MEDLINE]

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