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Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors.

Author information

1
Chemistry, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, United Kingdom.

Abstract

A range of novel N-terminal lipid-functionalized peptide nucleic acid (PNA) monomers have been prepared and their abilities to inhibit HIV-1 reverse transcriptase and integrase have been examined.

PMID:
18058537
DOI:
10.1080/15257770701513414
[Indexed for MEDLINE]

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