Format

Send to

Choose Destination
See comment in PubMed Commons below
Cytokine Growth Factor Rev. 2008 Feb;19(1):21-32. Epub 2007 Dec 3.

IFN regulation and functions in myeloid dendritic cells.

Author information

1
Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy. eliana.coccia@iss.it

Abstract

A central issue in dendritic cells (DC) biology is to understand how type I IFNs modulate the immuno-regulatory properties of DC. In this review I will address this issue in light of the recent experimental evidence on the expression and function of these cytokines in myeloid DC. This knowledge may have important therapeutic implications in infectious and neoplastic diseases and open new perspectives in the use of IFNs as vaccine adjuvants and in the development of DC-based vaccines.

PMID:
18054516
DOI:
10.1016/j.cytogfr.2007.10.005
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center