Format

Send to

Choose Destination
Immunol Lett. 2008 Jan 29;115(2):75-82. Epub 2007 Nov 20.

Intracellular mediators of CXCR4-dependent signaling in T cells.

Author information

1
Department of Evolutionary Biology, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy. patrussi2@unisi.it

Abstract

The signaling pathways induced in T lymphocytes by CXCR4-CXCL12 interaction, which lead to the cytoskeletal macro-rearrangements observable in migrating cells, are as yet largely uncharacterized. The aim of this review is to briefly summarize the current knowledge of the signaling machinery which controls the process of chemotaxis in CXCL12-stimulated T lymphocytes.

PMID:
18054087
DOI:
10.1016/j.imlet.2007.10.012
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center