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Ophthalmic Surg Lasers Imaging. 2007 Nov-Dec;38(6):497-9.

Leuprolide acetate and central retinal vein occlusion.

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Department of Ophthalmology, University of South Carolina, 4 Medical Park, Suite 300, Columbia, SC 29203, USA.


A 63-year-old man suffered a central retinal vein occlusion 2 months after he began taking leuprolide acetate for prostate cancer. Despite control for possible systemic hypertension (126/90 mm Hg) and mild hypercholesterolemia (total cholesterol level =246 mg/dL [range: 16 to 200 mg/dL], high-density lipoprotein level =67 mg/dL [range: 40 to 59 mg/dL], and low-density lipoprotein level =144 mg/dL [range: 0 to 130 mg/dL]), progression of the venous occlusive disease occurred. Leuprolide acetate, which is associated with thromboembolic events and diffuse intravascular coagulation, may be implicated in central retinal vein occlusion.

[Indexed for MEDLINE]

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