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Hautarzt. 2008 Jan;59(1):11-2, 14-7.

[Genital herpes and HSV transmission in HIV patients].

[Article in German]

Author information

1
Institut für Medizinische Virologie, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt, Paul-Ehrlich-Strasse 40, 60596 Frankfurt. rabenau@em.uni-frankfurt.de

Abstract

There is a bidirectional relationship between HSV-2 and HIV-1, both at the cellular level, as well as regarding transmission and even progression of HIV-1 infection. There is clear evidence that anti-herpetic therapy reduces the plasma and mucosal HIV-1 viral load, as well as transmission. Serologic testing for HSV-2 in patients with an increased HIV-1 risk, coupled with a better understanding of the interaction between the viruses and appropriate anti-herpetic suppression therapy could both reduce the HIV-1 transmission rate and help the individual with an HIV infection.

PMID:
18040650
DOI:
10.1007/s00105-007-1443-5
[Indexed for MEDLINE]
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