Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Neurosci. 2008 Jan;11(1):16-8. Epub 2007 Nov 25.

Recognition memory: opposite effects of hippocampal damage on recollection and familiarity.

Author information

  • 1Center for Memory and Brain, Boston University, Boston, MA 02215, USA.

Abstract

A major controversy in memory research concerns whether recognition is subdivided into distinct cognitive mechanisms of recollection and familiarity that are supported by different neural substrates. Here we developed a new associative recognition protocol for rats that enabled us to show that recollection is reduced, whereas familiarity is increased following hippocampal damage. These results provide strong evidence that these processes are qualitatively different and that the hippocampus supports recollection and not familiarity.

PMID:
18037884
PMCID:
PMC4053160
DOI:
10.1038/nn2016
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Support Center