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Trends Biotechnol. 2008 Jan;26(1):1-4. Epub 2007 Nov 26.

A better fluorescent protein for whole-body imaging.

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1
AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA 92111-3604, USA. all@anticancer.com

Abstract

Whole-body imaging with fluorescent proteins is a powerful technology with many applications in small animals. Brighter, red-shifted proteins can make whole-body imaging more sensitive owing to reduced absorption by tissues and less scatter. A new protein called Katushka has been isolated. It is the brightest known protein with emission at wavelengths longer than 620 nm. This new protein offers the potential for noninvasive whole-body imaging of numerous cellular and molecular processes in live animals.

PMID:
18037177
DOI:
10.1016/j.tibtech.2007.10.006
[Indexed for MEDLINE]
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