Format

Send to

Choose Destination
Expert Rev Cardiovasc Ther. 2007 Nov;5(6):1095-103.

Network-centered view of coronary artery disease.

Author information

1
Department of Medicine, University of California, Los Angeles, CA 90095-1679, USA. bbennett@mednet.ucla.edu

Abstract

Systems biology is an emerging field that attempts to examine multiple elements of a biologic system using techniques such as expression microarrays or proteomics. The goal of systems biology is to detect all the elements of a system and create an interaction network between these so that the system can be explained under specified conditions. In this review we discuss how systems-based approaches are being applied to cardiovascular disease, illustrating concepts, such as the integration of orthogonal datasets, coexpression networks and emergent properties.

PMID:
18035925
DOI:
10.1586/14779072.5.6.1095
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center