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Science. 2007 Nov 23;318(5854):1302-5.

Transposase-derived transcription factors regulate light signaling in Arabidopsis.

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1
Boyce Thompson Institute for Plant Research (BTI), Cornell University, Ithaca, NY 14853, USA.

Erratum in

  • Science. 2007 Dec 21;318(5858):1866.

Abstract

Plants use light to optimize growth and development. The photoreceptor phytochrome A (phyA) mediates various far-red light-induced responses. We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

PMID:
18033885
PMCID:
PMC2151751
DOI:
10.1126/science.1146281
[Indexed for MEDLINE]
Free PMC Article
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