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Nutr Neurosci. 2007 Jun-Aug;10(3-4):129-35.

Diet with LPP for renal patients increases daily energy expenditure and improves motor function in parkinsonian patients with motor fluctuations.

Author information

1
Parkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy. barichella@parkinson.it

Abstract

OBJECTIVE:

To establish whether a diet based on the usage of low-protein products for renal patients (LPP) is associated with higher energy expenditure (EE) than a free low-protein diet (NO-LPP) by calculating 24 h EE by indirect calorimetry using an electronic armband monitor.

DESIGN:

Randomized, cross-over, single-blind, pilot clinical trial performed comparing two different low-protein dietary regimens.

SUBJECTS:

Forty-two days with LPP and 42 days with NO-LPP regimen in six patients with Parkinson's disease with levodopa.

METHODS:

Monitoring patient response to two different nutritional schemes through indirect calorimetry (armband), BMI, Patient Global Improvement Scale.

RESULTS:

Mean total EE was 1731 +/- 265 kcal/day with NO-LPP vs. 1903 +/- 265 kcal/day with LPP (p = 0.02).

CONCLUSIONS:

The usage of LPP increases EE and improves motor function in PD patients to a greater extent than NO-LPP dietary regimen. Calorie intake should be increased to prevent malnutrition in the long-term.

PMID:
18019394
PMCID:
PMC2413077
DOI:
10.1080/10284150701414046
[Indexed for MEDLINE]
Free PMC Article

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