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Biotechniques. 2007 Oct;43(4):ii-v.

Short tandem repeat typing technologies used in human identity testing.

Author information

1
Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8311, USA. john.butler@nist.gov

Abstract

Short tandem repeat (STR) typing methods are widely used today for human identity testing applications including forensic DNA analysis. Following multiplex PCR amplification, DNA samples containing the length-variant STR alleles are typically separated by capillary electrophoresis and genotyped by comparison to an allelic ladder supplied with a commercial kit. This article offers a brief perspective on the technologies and issues involved in STR typing.

PMID:
18019344
[Indexed for MEDLINE]

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