1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes

David Díez; M Templo Benéitez; Isidro S Marcos; N M Garrido; P Basabe; Julio G Urones

doi:10.3390/90500323

1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes

Molecules. 2004 Apr 30;9(5):323-9. doi: 10.3390/90500323.

Authors

David Díez¹, M Templo Benéitez, Isidro S Marcos, N M Garrido, P Basabe, Julio G Urones

Affiliation

¹ Dpto. de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain. ddm@usal.es

Abstract

A method to synthesize chiral 2,3,4-trisusbtituted tetrahydrothiophenes in both enantiomerically pure forms starting from 1-hydroxymethyl-4-phenylsulfonylbutadiene is described.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Butadienes / chemistry*
Models, Chemical
Molecular Structure
Stereoisomerism
Sulfones / chemistry*
Thiophenes / chemical synthesis*
Thiophenes / chemistry

Substances

1-hydroxymethyl-4-phenylsulfonylbutadiene
Butadienes
Sulfones
Thiophenes
tetrahydrothiophene