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Semi-automated clustering of gene expression data sets.

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1
Electronics and Telecommunications Research Institute, 161, Gajeong-dong, Yuseong-gu, Daejeon, 305-700, Republic of KOREA. kimmh@etri.re.kr

Abstract

Clustering, as one of key analysis tools for gene expression data sets, attempts to discover groups of genes having similar expression patterns. In order to get a reasonable biological interpretation, it is desirable that a clustering result be accurate enough. However, conventional clustering methods do not always meet this demand since they require the exact tuning of input parameters and cluster centers for an acceptable quality of result. Through an intuitive user interaction, UI-Cluster solves the problem mentioned above, and yields better clustering results.

PMID:
18003036
DOI:
10.1109/IEMBS.2007.4353370
[Indexed for MEDLINE]
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