Format

Send to

Choose Destination
Genome Biol. 2007;8(10):112.

Making the most of high-throughput protein-interaction data.

Author information

1
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. rgentlem@fhcrc.org

Abstract

We review the estimation of coverage and error rate in high-throughput protein-protein interaction datasets and argue that reports of the low quality of such data are to a substantial extent based on misinterpretations. Probabilistic statistical models and methods can be used to estimate properties of interest and to make the best use of the available data.

PMID:
18001486
PMCID:
PMC2246275
DOI:
10.1186/gb-2007-8-10-112
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center