Cerebellar tissue from several ET cases showing two torpedoes in close proximity (top, LH and E 200× magnification), (bottom left, LH and E 400× magnification), and one torpedo (bottom right, Bielschowsky-stained, 400× magnification). (Permissions for Figure 2 as follows: Figure 2, top: Archives of Neurology, 2006, volume 63, page 1191, Copyright © 2006, American Medical Association. All rights reserved. Figure 2, bottom left: Louis et al. Neuropathologic findings in essential tremor. Neurology, 2006;66:1756–1759.)