Format

Send to

Choose Destination
Curr Opin Microbiol. 2007 Dec;10(6):630-7. Epub 2007 Nov 9.

Advantages and mechanisms of polarity and cell shape determination in Caulobacter crescentus.

Author information

1
Department of Biology, Indiana University, 1001 East Third Street, Bloomington, IN 47405-3700, USA.

Abstract

The tremendous diversity of bacterial cell shapes and the targeting of proteins and macromolecular complexes to specific subcellular sites strongly suggest that cellular organization provides important advantages to bacteria in their environment. Key advances have been made in the understanding of the mechanism and function of polarity and cell shape by studying the aquatic bacterium Caulobacter crescentus, whose cell cycle progression involves the ordered synthesis of different polar structures, and culminates in the biosynthesis of a thin polar cell envelope extension called the stalk. Recent results indicate that the important function of polar development is to maximize cell attachment to surfaces and to improve nutrient uptake by nonmotile and attached cells. Major progress has been made in understanding the regulatory network that coordinates polar development and morphogenesis and the role of polar localization of regulatory proteins.

PMID:
17997127
PMCID:
PMC2175029
DOI:
10.1016/j.mib.2007.09.007
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center