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Health Phys. 2007 Dec;93(6):701-4.

Estimating radiation dose from time to emesis and lymphocyte depletion.

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1
WriteSolutions, 155 Montana Avenue, Oak Ridge, TN 37830, USA. writesolutions@bellsouth.net

Abstract

Lymphocyte depletion kinetics and time to emesis have previously been shown to correlate with radiation dose. However, the method for estimating dose from lymphocyte counts was cumbersome, and a tabulation of estimated dose vs. time to emesis published by the International Atomic Energy Agency did not agree well with a regression of data from many (>100) radiation accident cases. The time-to-emesis data have been reanalyzed, and the new regression corroborates the previously published table. Also, dose estimation from post-exposure lymphocyte counts has been simplified and no longer requires serial calculations. Instead, dose can be estimated by a simple table lookup, given the ratio of two lymphocyte counts and the time between blood samples.

[Indexed for MEDLINE]

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