Comment on "A G protein coupled receptor is a plasma membrane receptor for the plant hormone abscisic acid"

Science. 2007 Nov 9;318(5852):914; author reply 914. doi: 10.1126/science.1143230.

Abstract

Liu et al. (Reports, 23 March 2007, p. 1712) reported that the Arabidopsis thaliana gene GCR2 encodes a seven-transmembrane, G protein-coupled receptor for abscisic acid. We argue that GCR2 is not likely to be a transmembrane protein nor a G protein-coupled receptor. Instead, GCR2 is most likely a plant homolog of bacterial lanthionine synthetases.

Publication types

  • Comment

MeSH terms

  • Abscisic Acid / metabolism*
  • Algorithms
  • Amino Acid Sequence
  • Arabidopsis / chemistry
  • Arabidopsis / metabolism*
  • Arabidopsis Proteins / chemistry*
  • Arabidopsis Proteins / isolation & purification
  • Arabidopsis Proteins / metabolism*
  • GTP-Binding Protein alpha Subunits / metabolism
  • Hydro-Lyases / chemistry*
  • Hydro-Lyases / metabolism
  • Models, Molecular
  • Molecular Sequence Data
  • Multienzyme Complexes / chemistry*
  • Multienzyme Complexes / metabolism
  • Plant Growth Regulators / metabolism*
  • Protein Binding
  • Protein Folding
  • Protein Structure, Secondary
  • Protein Structure, Tertiary
  • Receptors, G-Protein-Coupled / chemistry*
  • Receptors, G-Protein-Coupled / isolation & purification
  • Receptors, G-Protein-Coupled / metabolism*
  • Recombinant Proteins / chemistry
  • Recombinant Proteins / metabolism
  • Sequence Alignment

Substances

  • Arabidopsis Proteins
  • GCR2 protein, Arabidopsis
  • GPA1 protein, Arabidopsis
  • GTP-Binding Protein alpha Subunits
  • Multienzyme Complexes
  • Plant Growth Regulators
  • Receptors, G-Protein-Coupled
  • Recombinant Proteins
  • Abscisic Acid
  • Hydro-Lyases
  • lanthionine synthase