The Suicide Opinion Questionnaire (SOQ) was administered to two samples of medical school students, from Japan (n = 80 males and 20 females) and the United States (n = 80 males and 20 females). A MANOVA followed by univariate tests indicated significant differences on the Right to die, Normality, and Aggression scales between Japanese and United States students, and significant gender differences on the Religion and Impulsivity scales. No gender by nationality interaction was obtained. An analysis of the individual SOQ items revealed substantial differences between Japanese and United States medical students in their views on suicide.