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Cell Metab. 2007 Nov;6(5):339-40.

AMPK and SNF1: Snuffing Out Stress.

Author information

1
Division of Molecular Physiology, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK. d.g.hardie@dundee.ac.uk

Abstract

AMP-activated protein kinase (AMPK) has attracted much attention for its key role in energy homeostasis. Three new papers providing structural information on mammalian and yeast AMPK homologs give insights into the binding of the regulatory nucleotides AMP and ATP and how mutations are associated with cardiac glycogen storage disorders.

PMID:
17983576
PMCID:
PMC2080653
DOI:
10.1016/j.cmet.2007.10.001
[Indexed for MEDLINE]
Free PMC Article

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