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Clin Calcium. 2007 Nov;17(11):1693-9.

[Clinical application of vitamin K for hepatocellular carcinoma].

[Article in Japanese]

Author information

1
Saga Medical School, Department of Internal Medicine.

Abstract

Despite recent progress in diagnosis and therapy, hepatocellular carcinoma (HCC) remains among the cancers with the poorest prognoses. Vitamin K (VK) have been shown to suppress the growth of HCC cells. Long-term administration of VK(2) has established its clinical safety, but it does not appear to exhibit marked anti-tumor effects when administered alone. For more effective use of VK against HCC, co-administration of VK(2) with other proven anticancer agents or development of a new VK preparation with a modified side-chain should be investigated in the future.

PMID:
17982189
DOI:
CliCa071116931699
[Indexed for MEDLINE]

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