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Laryngorhinootologie. 2007 Nov;86(11):804-8, quiz 809-13.

[ACE-inhibitor induced angioedema].

[Article in German]

Author information

1
Hals-Nasen-Ohrenklinik und Poliklinik, Klinikum rechts der Isar der Technischen Universität München, München, Germany. basmurat@web.de

Abstract

ACE-inhibitor induced angioedema is a non-allergic drug-related side effect. Inhibited bradykinin degradation leads to an unphysiological enhanced bradykinin plasma level with vascular leakage and, consequently, to angioedema. ACE-inhibitor induced angioedema develop rapidly in the head and neck region. Typical sites of manifestation are lips, tongue, and larynx. Novel pharmacotherapies may allow a causal treatment of the ACE-inhibitor induced angioedema in the future.

PMID:
17966084
DOI:
10.1055/s-2007-966932
[Indexed for MEDLINE]

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