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Acc Chem Res. 2007 Dec;40(12):1309-19. Epub 2007 Oct 26.

Hydrogenation processes in the synthesis of perfumery ingredients.

Author information

1
Synthesis, Corporate R&D Division, Firmenich SA, PO Box 239, CH-1211 Geneva 8, Switzerland. lionel.saudan@firmenich.com

Abstract

Homogeneous catalytic hydrogenation has played an important role in the development of modern organic synthesis. Indeed, the discovery of highly regio- and stereoselective catalysts for C=C and C=O bonds reductions has allowed the efficient synthesis of optically active compounds. As the fragrance industry has turned to synthetic ingredients to fulfill the need for novel, cost-effective, and environment-friendly products, the use of catalytic processes are more and more in demand. In this Account, we thus highlight the application of catalytic hydrogenation in the synthesis of fragrance ingredients.

PMID:
17960898
DOI:
10.1021/ar700140m

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