Abstract
Antibodies in the sera of patients with lacaziosis recognized an approximately 193-kDa antigen and other Lacazia loboi antigens. Paracoccidioides brasiliensis gp43 antigen was detected by all evaluated sera, but they failed to detect a protein with the same molecular mass in L. loboi extracts. This study is the first to examine the humoral response to L. loboi antigens by using multiple host sera.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Antibodies, Fungal / immunology
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Antibodies, Fungal / isolation & purification
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Antigens, Fungal / blood*
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Antigens, Fungal / immunology
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Antigens, Fungal / isolation & purification
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Blotting, Western / methods*
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Bottle-Nosed Dolphin
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Fungal Proteins / blood
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Fungal Proteins / immunology
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Glycoproteins / blood
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Glycoproteins / immunology
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Humans
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Immunoglobulin G / immunology
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Mice
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Mycoses / blood*
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Mycoses / diagnosis
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Mycoses / immunology
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Onygenales / immunology*
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Onygenales / isolation & purification
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Paracoccidioides / immunology
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Paracoccidioides / isolation & purification
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Paracoccidioidomycosis / blood
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Paracoccidioidomycosis / diagnosis
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Paracoccidioidomycosis / microbiology
Substances
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43 kDa protein, Paracoccidioides
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Antibodies, Fungal
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Antigens, Fungal
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Fungal Proteins
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Glycoproteins
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Immunoglobulin G