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Annu Rev Nurs Res. 2007;25:191-217.

Genomics and proteomics methodologies for vulnerable populations research.

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  • 1Uniformed Services University of the Health Sciences, Graduate School of Nursing, Bethesda, Maryland, USA.


This chapter describes common genomic and proteomic methods and their application to the study of vulnerable population groups. The International HapMap project is discussed in relation to unique Haplotype single nucleotide polymorphisms (htSNPs) in population groups. In addition, studies, which have used these methods to investigate aging, ethnic, and racial specific conditions, as well as psychiatric diseases, are reviewed. Advantages and limitations of various genomic and proteomic approaches are discussed in relation to population admixture and sample selection.

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