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Comparative study of silicone-hydrogel contact lenses surfaces before and after wear using atomic force microscopy.

Author information

1
Department of Physics (Optometry), School of Sciences, University of Minho, Portugal. mlira@fisica.uminho.pt

Abstract

PURPOSE:

The aim of this study was to analyze surface changes of three silicone-hydrogel contact lenses after daily wear. The lenses used in this study were balafilcon A, lotrafilcon B (both surface-treated), and galyfilcon A (non surface-treated).

METHODS:

To understand how and where proteins, lipids, and other contaminants change contact lenses, surface roughness was assessed through Atomic Force Microscopy Tapping Mode. Roughness parameters were Mean Surface roughness (R(a)), Mean-square-roughness (R(q)), and Maximum roughness (R(max)). The surface topography of unworn and worn lenses was also mapped in great detail.

RESULTS:

Contact lenses roughness parameters exhibited different values before and after wear and the surface appearance also changed. After wear, balafilcon A and galyfilcon A showed a significant increase on surface roughness parameters, being this increase more accentuated to galyfilcon A. In lotrafilcon B materials no significant changes were observed with wear.

CONCLUSIONS:

The present study suggests that surface treatment of silicone-hydrogel contact lenses can play a role in the prevention of a significant increase in roughness, and contribute to the better clinical tolerance of these lenses.

PMID:
17957701
DOI:
10.1002/jbm.b.30954
[Indexed for MEDLINE]

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