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Cell. 2007 Oct 19;131(2):230-1.

The chromosomal passenger complex: one for all and all for one.

Author information

1
Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Mayfield Road, Edinburgh EH9 3JR, UK.

Abstract

The chromosomal passenger complex-composed of Aurora B kinase and its regulatory subunits INCENP, Survivin, and Borealin-modulates multiple events during mitosis. In this issue, Jeyaprakash et al. (2007) report the crystal structure of the regulatory subunit complex and reveal how interactions between these proteins promote the targeting and function of the chromosomal passenger complex during mitosis.

PMID:
17956723
DOI:
10.1016/j.cell.2007.10.002
[Indexed for MEDLINE]
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