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J Headache Pain. 2007 Oct;8(5):277-82. Epub 2007 Oct 23.

Cluster headache and intracranial aneurysm.

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  • 1Division of Neurology and Neurosurgery, Department of Neuropsychiatry, Federal University of Pernambuco, 50670-420, Recife, Pernambuco, Brazil.


In the present study we describe the cases of two patients with cluster-like headache related to intracranial carotid artery aneurysm. One of these patients responded to verapamil prescription with headache resolution. In both cases the surgical clipping of the aneurysm resolved the cluster pain. These findings strongly suggest a pathophysiological link between the two conditions. The authors discuss the potential pathophysiological mechanisms underlying cluster-like headache due to intracranial carotid artery aneurysm.

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