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Emerg Infect Dis. 2007 Aug;13(8):1189-94.

High prevalence of tuberculosis in previously treated patients, Cape Town, South Africa.

Author information

1
Desmond Tutu Centre, Stellenbosch University, Cape Town, South Africa. denboons@kncvtbc.nl

Abstract

The tuberculosis (TB) notification rate is high and increasing in 2 communities in Cape Town, South Africa. In 2002, we conducted a prevalence survey among adults > or = 15 years of age to determine the TB prevalence rate; 15% of households in these communities were randomly sampled. All persons living in sampled households were eligible for chest radiography and sputum examination. Of the 3,483 adults who completed a questionnaire, 2,608 underwent chest radiography and sputum examination. We detected 26 bacteriologically confirmed TB cases and a prevalence of 10.0/1,000 (95% confidence interval [CI] 6.2-13.8 per 1,000). We found 18 patients with smear-positive TB, of whom 8 were new patients (3.1/1,000, 95% CI 0.9-5.1/1,000). More than half of patients with smear-positive TB (10, 56%) had previously been treated. Such patients may contribute to transmission of Mycobacterium tuberculosis and the high TB prevalence rate. Successful treatment of TB patients must be a priority.

PMID:
17953090
PMCID:
PMC2828063
DOI:
10.3201/eid1308.051327
[Indexed for MEDLINE]
Free PMC Article

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