Format

Send to

Choose Destination
Biol Trace Elem Res. 2008 Mar;121(3):243-8. Epub 2007 Oct 19.

Effects of restraint stress on iron, zinc, calcium, and magnesium whole blood levels in mice.

Author information

1
College of Medical Laboratory, Dalian Medical University, Dalian, China.

Abstract

OBJECTIVE:

Study the effects of acute and chronic restraint stress on the whole blood concentrations of iron (Fe), zinc (Zn), calcium (Ca), and magnesium (Mg) in mice.

MATERIALS AND METHODS:

Single or repeat restraints were applied to mice to induce acute or chronic stress. The levels of elements in whole blood were determined by flame atomic absorption spectrometry.

RESULTS:

The levels of Fe, Zn, Ca, and Mg in blood in the acute-stress group were 351, 5.05, 60, and 44 microg/ml, respectively, and those in the corresponding control group were 391, 5.90, 59, and 45 microg/ml, respectively. The levels of blood Fe, Zn, Ca, and Mg in the chronic-stress group were 291, 3.62, 59, and 40 microg/ml, respectively, and those in the corresponding control group were 393, 4.82, 48, and 43 microg/ml, respectively. The levels of Fe and Zn in the blood of both the acute-stress and the chronic-stress groups were significantly lower (P < 0.05) than that in the control groups. The Ca level in whole blood was significantly (P < 0.05) higher in the chronic-stress group than that in the control group.

CONCLUSION:

Acute and chronic restraint stress can cause changes in blood levels of Fe and Zn in mice.

PMID:
17952382
DOI:
10.1007/s12011-007-8047-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center