Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Neurophysiol. 2007 Dec;118(12):2620-4. Epub 2007 Oct 18.

A brush stimulator for functional brain imaging.

Author information

1
Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, Brain Research Unit, Otakaari 3, 02015 HUT, Espoo, Finland. veikko@neuro.hut.fi

Abstract

OBJECTIVE:

To describe a novel non-magnetic hand-held device to stimulate various parts of the skin and to evaluate its performance in magnetoencephalographic (MEG) recordings.

METHODS:

The hand-held part of the device consists of an optic fiber bundle that forms a small brush. Half of the fibers emit modulated red light and the other half detect the reflected light from the skin so that the brush-to-skin contact is detected by means of reflectance.

RESULTS:

Light tapping of the back of the hand at the innervation area of the radial nerve elicited clear responses in all 10 subjects studied, with the main deflections peaking 40-70 ms after the stimulus. The earliest responses, obtained with a higher number of averaged trials, peaked 27-28 ms after the tap to the left hand dorsum. Source analysis of the MEG signals indicated neuronal sources at the primary somatosensory (SI) cortex, with a clear somatotopical order for face vs. hand.

CONCLUSIONS:

The device seems feasible for both MEG and functional magnetic resonance imaging experiments to address functional anatomy of the human somatosensory system with a real-life like stimulation.

SIGNIFICANCE:

Non-magnetic and artefact-free tactile stimulator with a selective stimulus offers new possibilities for experimental designs to study the human mechanoreceptor system.

PMID:
17950032
DOI:
10.1016/j.clinph.2007.08.024
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center