Format

Send to

Choose Destination
See comment in PubMed Commons below
Dev Dyn. 2007 Dec;236(12):3343-57.

Caenorhabditis elegans germ line: a model for stem cell biology.

Author information

1
New York University School of Medicine, Developmental Genetics, Skirball Institute for Biomolecular Medicine, Department of Pathology, Helen and Martin Kimmel Center for Stem Cell Biology, New York, New York 10016, USA. jhubbard@saturn.med.nyu.edu

Abstract

Like many stem cell systems, the Caenorhabditis elegans germ line contains a self-renewing germ cell population that is maintained by a niche. Although the exact cellular mechanism for self-renewal is not yet known, three recent studies shed considerable light on the cell cycle behavior of germ cells, including a support for significant and plastic renewal potential. This review brings together the results of the three recent cell-based studies, places them in the context of previous work, and discusses future perspectives for the field.

PMID:
17948315
PMCID:
PMC2949268
DOI:
10.1002/dvdy.21335
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley Icon for PubMed Central
    Loading ...
    Support Center