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Int J Prosthodont. 2007 Sep-Oct;20(5):504-6.

Susceptibility of candida isolates from denture-related stomatitis to antifungal agents in vitro.

Author information

1
Department of Prosthetic Dentistry, Poznan University of Medical Sciences, Poland. badb@mp.pl

Abstract

The aim of this study was to determine the susceptibility of Candida isolates obtained from patients with Candida-associated denture stomatitis to 4 antimycotics. Antifungal susceptibility was assayed using the ATB-Fungus-2INT test. A total of 120 Candida strains were identified: C albicans (59.2%), C glabrata (20%), C tropicalis (12.5%), and C parapsilosis (8.3%). Amphotericin B, 5-fluorocytosine, fluconazole, and itraconazole were effective against 100%, 98.6%, 88.7%, and 87.3% of C albicans and 79.6%, 77.6%, 71.4%, and 79.6% of the other Candida strains, respectively. The identification of candidal strains and determination of their susceptibility to antifungals may improve the management of Candida-associated denture stomatitis.

PMID:
17944341
[Indexed for MEDLINE]

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