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Cancer Cell. 2007 Oct;12(4):300-1.

Inflammation and cancer: a double-edged sword.

Author information

1
Centre for Translational Oncology, Institute of Cancer and CR-UK Clinical Centre, Barts and The London Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK. t.hagemann@qmul.ac.uk

Abstract

Recent literature has highlighted an important role of inflammation in promoting cancer. However, the immune system can also play a central role in protecting the body against cancer as well as infection, although its role in cancer is not well understood. A study published in the September issue of Nature Medicine adds a new twist to the role of inflammation in cancer. Apetoh et al. describe how activation of innate immunity after conventional radiation or chemotherapy can trigger protective antitumor immunity.

PMID:
17936555
PMCID:
PMC2592547
DOI:
10.1016/j.ccr.2007.10.005
[Indexed for MEDLINE]
Free PMC Article

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