Send to

Choose Destination
Trends Plant Sci. 2007 Nov;12(11):514-21. Epub 2007 Oct 22.

Phytochrome Interacting Factors: central players in phytochrome-mediated light signaling networks.

Author information

Section of Molecular Cell and Developmental Biology and The Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.


To adapt to the surrounding environment, plants constantly monitor and respond to changes in the red and far-red regions of the light spectrum through the phytochrome family of photoreceptors. Extensive efforts using genetic, molecular and photobiological techniques have led to the identification of a group of basic helix-loop-helix transcription factors called the Phytochrome Interacting Factors, PIFs, which directly bind to the photoactivated phytochromes. Members of the PIF family have been shown to control light-regulated gene expression directly and indirectly. PIF1, PIF3, PIF4 and PIF5 are degraded in response to light signals, and physical interaction of PIF3 with phytochromes is necessary for the light-induced phosphorylation and degradation of PIF3. PIFs constitute an excellent model for the investigation of the biochemical mechanisms of signal transfer from photoactivated phytochromes and the light-regulation of gene expression that controls photomorphogenesis in plants.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center