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Sci STKE. 2007 Oct 9;2007(407):cm4.

Cytokinin signaling pathway.

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Department of Molecular Biology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA.


Cytokinins are key regulators of a large number of processes in plant development, which is highly plastic and adaptive, and remarkably resilient and self-perpetuating. Cytokinin signaling involves a multistep two-component system, also called a phosphorelay signaling system. Genes encoding the central components to build the cytokinin phosphorelay system are found in diverse plant species, resulting in the establishment of a canonical model of cytokinin signaling that is likely representative and conserved in plants. The cytokinin signaling pathway can be modulated by nutrients, stress, and other hormones, and is integrated into a signaling network in both shoots and roots.

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