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Am J Emerg Med. 2007 Oct;25(8):918-24.

An assessment of the association of bispectral index with 2 clinical sedation scales for monitoring depth of procedural sedation.

Author information

1
Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. chsweave@iupui.edu

Abstract

OBJECTIVE:

We conducted a study to assess the correlation of bispectral index (BIS) to 2 clinical sedation scales.

METHODS:

This was a prospective, observational study. The BIS number was recorded at baseline and every 30 seconds. One investigator separately monitored the patients for depth of sedation using the Observer's Assessment of Alertness/Sedation and the Continuum of Depth of Sedation scales.

RESULTS:

During the 6-month period, 75 patients were enrolled. The Spearman correlation between the BIS and the Observer's Assessment of Alertness/Sedation was 0.59 (95% confidence interval [CI], 0.44-0.74). The Spearman correlation between the BIS and the Continuum of Depth of Sedation was 0.53 (95% CI, 0.36-0.70). The mean minimum BIS for patients without a complication was 70 (SD, 15.9) compared with 68 (SD, 12.9) for patients with a complication (difference = 2; 95% CI, -7-11).

CONCLUSIONS:

Our study demonstrated moderate correlation between BIS and the 2 clinical sedation scales. The correlation is not strong enough to be used reliably in a clinical setting. The mean minimum BIS scores were not significantly different for those with sedation complications vs those without complications.

PMID:
17920977
DOI:
10.1016/j.ajem.2007.02.042
[Indexed for MEDLINE]
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