Format

Send to

Choose Destination
See comment in PubMed Commons below
Trends Microbiol. 2007 Oct;15(10):469-75. Epub 2007 Oct 24.

Microtiter plates as mini-bioreactors: miniaturization of fermentation methods.

Author information

1
Enzyscreen, Biopartner Center Leiden, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands. duetz@enzyscreen.com

Abstract

In the past decade, the use of microtiter plates for microbial growth has become widespread, particularly in industry. In parallel, research in academia has provided a thorough insight into the complex relation between well dimensions, culture volumes, orbital shaking conditions and surface tension on the one hand, and oxygen-transfer rates and degrees of mixing on the other. In this review, I will discuss these fundamental issues and describe the current applications of microtiter plates in microbiology. Microtiter plates can now be considered a mature alternative to Erlenmeyer shake flasks.

PMID:
17920276
DOI:
10.1016/j.tim.2007.09.004
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center