Format

Send to

Choose Destination
Nat Clin Pract Neurol. 2007 Oct;3(10):581-4.

A case of celiac disease mimicking amyotrophic lateral sclerosis.

Author information

1
Department of Neurology, John Radcliffe Hospital, Oxford, UK.

Abstract

BACKGROUND:

A 44-year-old male presented to a general neurology clinic with a 6-month history of progressive right-sided spastic hemiparesis without sensory symptoms or signs. The thigh muscle in the affected leg showed signs of wasting. The patient had a remote family history of celiac disease.

INVESTIGATIONS:

Neurological examination, neurophysiological studies, brain MRI scan, routine blood tests, duodenal biopsy, cerebrospinal fluid analysis including polymerase chain reaction test for JC virus DNA, serological testing for HIV and for the presence of serum antibodies to endomysium, gliadin and tissue transglutaminase.

DIAGNOSIS:

Celiac disease with neurological involvement, mimicking amyotrophic lateral sclerosis.

MANAGEMENT:

Strict gluten-free diet.

PMID:
17914346
DOI:
10.1038/ncpneuro0631
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center