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Trends Cell Biol. 2007 Oct;17(10):474-84.

Peroxisomal dynamics.

Author information

1
Ruhr-Universität Bochum, Medizinische Fakultät, Institut für Physiologische Chemie, Abteilung für Systembiochemie, Universitätsstr. 150, D-44780 Bochum, Germany.

Abstract

Peroxisomes are a dynamic compartment in almost all eukaryotic cells and have diverse metabolic roles in response to environmental changes and cellular demands. The accompanying changes in enzyme content or abundance of peroxisomes are accomplished by dynamically operating membrane- and matrix-protein transport machineries. This review discusses recent progress in understanding peroxisomal proliferation and maintenance, insertion of peroxisomal membrane proteins, compartmentalization of peroxisomal matrix proteins and selective degradation of peroxisomes via pexophagy.

PMID:
17913497
DOI:
10.1016/j.tcb.2007.06.009
[Indexed for MEDLINE]

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