Format

Send to

Choose Destination
Nature. 1976 May 6;261(5555):26-9.

Production of yeast alcohol dehydrogenase isoenzymes by selection.

Abstract

Mutants of yeast alcohol dehydrogenase have been produced that protect the cell against the poisonous aldehyde acrolein by increasing the NADH-NAD ratio. The altered properties include changes both in binding constants and in cooperativity. Such mutants may be useful in exploring the nature of adaptation at the molecular level.

PMID:
179008
DOI:
10.1038/261026a0
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center