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Virchows Arch. 2007 Nov;451(5):863-9. Epub 2007 Sep 27.

Pancreatic intraductal papillary-mucinous neoplasms: a new and evolving entity.

Author information

1
Institute of Pathology, Faculty of Medicine and Biology, University of Lausanne, Lausanne, Switzerland.

Abstract

For a long time, intraductal tumors of the pancreas were neglected because they were misdiagnosed as mucinous cystadenocarcinoma, ordinary ductal adenocarcinoma, or chronic pancreatitis. Only in recent years have they been recognized as clinical and pathological entities. Most common are the intraductal papillary-mucinous neoplasms. Although they show an adenoma-carcinoma sequence, they have proved to have a more favorable prognosis than ductal adenocarcinoma, when resected in a preinvasive state. Recently, it has become clear that they constitute a heterogeneous group with at least four subtypes. Their stratification reveals that the various intraductal papillary-mucinous neoplasm subtypes have different biological properties with different prognostic implications.

PMID:
17899180
PMCID:
PMC2063564
DOI:
10.1007/s00428-007-0512-6
[Indexed for MEDLINE]
Free PMC Article

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