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Lett Appl Microbiol. 2007 Oct;45(4):349-57.

Relationship between mycobacteria and amoebae: ecological and epidemiological concerns.

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STERIS Laboratory, CEA/DSV/IMETI/SEPIA, 18 route du Panorama, 92260 Fontenay-aux-Roses, France.


Since the discovery that Legionella pneumophila can survive and grow within free-living amoebae, there has been an increasing number of microbial species shown to have similar relationships. These include many bacterial species, fungi, other protozoa (e.g. Cryptosporidium) and viruses. Among bacteria, mycobacteria are of particular importance because of their role in human and animal infections. This review will consider the progress made in understanding the relationships between mycobacteria and amoebae, and their consequences in terms of ecology and epidemiology.

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