Abstract
A 43-year-old man presented with acute bilateral visual loss. Ophthalmologic examination revealed no light perception in the right eye and a visual acuity of 20/50 in the left eye with a right afferent pupillary defect. Ophthalmoscopic examination was normal. Brain MRI showed an intracranial but extra-axial mass in the floor of the anterior cranial fossa extending along the olfactory groove and into the sinonasal vault. Endoscopic biopsy showed a high-grade neoplasm consistent with sinonasal undifferentiated carcinoma. This case report highlights an unusual clinical presentation for this rare and aggressive neoplasm.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Biomarkers, Tumor
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Biopsy
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Carcinoma / complications*
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Carcinoma / pathology
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Carcinoma / physiopathology
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Cranial Fossa, Anterior / pathology
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Cranial Fossa, Anterior / physiopathology
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Fatal Outcome
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Functional Laterality
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Humans
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Magnetic Resonance Imaging
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Male
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Nasal Cavity / pathology
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Nasal Cavity / physiopathology
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Neoplasm Metastasis / pathology
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Optic Nerve / pathology
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Optic Nerve / physiopathology
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Optic Nerve Diseases / etiology*
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Optic Nerve Diseases / pathology
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Optic Nerve Diseases / physiopathology
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Orbit / pathology
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Orbit / physiopathology
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Paranasal Sinus Neoplasms / complications*
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Paranasal Sinus Neoplasms / pathology
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Paranasal Sinus Neoplasms / physiopathology
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Paranasal Sinuses / pathology
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Paranasal Sinuses / physiopathology
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Radiotherapy
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Treatment Failure
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Vision, Low / etiology*
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Vision, Low / pathology
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Vision, Low / physiopathology