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J Neurosurg Anesthesiol. 2007 Oct;19(4):273-9.

The use of the excimer laser-assisted anastomosis technique alleviates neuroanesthesia during cerebral high-flow revascularization.

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Department of Anesthesiology, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany.


In patients with complex intracranial aneurysms or skull base tumors, parent vessel occlusion and flow replacement by high-flow bypass surgery is a demanding therapy, both for the neurosurgeon and the neuroanesthesiologist. One reason for this is the need for prolonged temporary occlusion of a major cerebral artery, which carries a high risk of perioperative ischemia and necessitates versatile neuroprotective measures during anesthesia. Recently, a novel excimer laser-assisted nonocclusive anastomosis (ELANA) technique has been introduced, circumventing the need for temporary occlusion of cerebral vessels. We hypothesized that the use of this ELANA technique would facilitate also the neuroanesthesiologic management of these patients. To test this, we reviewed the details of the neuroanesthesiologic management of patients undergoing ELANA high-flow bypass surgery at our institution. Twenty-nine patients with giant aneurysms (n=27) or skull base tumor (n=2) who were undergoing parent vessel occlusion and permanent flow replacement by high-flow bypass surgery using the ELANA technique were investigated retrospectively. The records of the patients were analyzed for induction and maintenance of anesthesia, fluid therapy, transfusion requirements, hemodynamic parameters, and brain protective strategies. Although we are not able to provide a sufficient body of cohort data to compare the neuroanesthesiologic management of patients undergoing the conventional anastomosis technique with management using the ELANA technique, in each of our reported cases the conventional anastomosis technique would have entailed a high probability of prolonged temporary occlusion that would, in turn, have warranted intensive brain-protective strategies. The observation that use of the ELANA technique precluded the necessity of brain-protective strategies without entailing perioperative cerebral infarction suggests that the ELANA technique supports the neurosurgeon in creating difficult permanent intracranial anastomoses and also facilitates neuroanesthesiologic management of patients undergoing cerebral high-flow revascularization procedures.

[Indexed for MEDLINE]

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