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Arq Bras Endocrinol Metabol. 2007 Jul;51(5):813-7.

[Cervical lymph nodes metastases in patients with differentiated thyroid cancer].

[Article in Portuguese]

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Divisão de Endocrinologia, Escola Paulista de Medicina, UNIFESP, São Paulo, SP, Brazil.


Loco-regional recurrences of the differentiated thyroid cancer have been reported to be located in cervical lymph nodes in 60-75% of cases. The widespread use of neck ultrasonography (US) during the follow-up of patients with papillary thyroid carcinoma (PTC) has led to the discovery of small cervical lymph nodes (LN). Although US has a high sensitivity for diagnosing LN, fine needle aspiration biopsy (FNA) and measurement of thyroglobulin in fine needle aspirates (FNA-Tg) have proven to be invaluable tools. The aim of this paper is to review the importance of the early diagnosis of lymph node metastases in the follow-up of patients with differentiated thyroid cancer.

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